• 咨询热线
    客服服务热线 13671568941/15317326293
  • 在线咨询
  • 微信客服
    微信客服
  • 公众号
    扫码关注公众号

Hexamethylene bisacetamide

CAS No. 3073-59-4

Hexamethylene bisacetamide ( HMBA;NSC 95580 )

产品货号. M13980 CAS No. 3073-59-4

A cell differentiation inducer that inhibits activation of NF-κB function, Akt and ERK/MAPK cascade.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
25MG ¥340 有现货
50MG ¥535 有现货
100MG ¥737 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    Hexamethylene bisacetamide
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    A cell differentiation inducer that inhibits activation of NF-κB function, Akt and ERK/MAPK cascade.
  • 产品描述
    A cell differentiation inducer that inhibits activation of NF-κB function, Akt and ERK/MAPK cascade; causes MEL cell differentiation by acting as a selective BD2 (bromodomain 2) inhibitor, kills Myc-induced lymphoma cells in vitro and in vivo; also is a small molecule inducer of HEXIM1 expression, inhibits the metastasis of breast cancer to lung in PyMT mice.
  • 同义词
    HMBA;NSC 95580
  • 通路
    Chromatin/Epigenetic
  • 靶点
    Bromodomain
  • 受体
    Bromodomain
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    3073-59-4
  • 分子量
    200.28
  • 分子式
    C10H20N2O2
  • 纯度
    >98% (HPLC)
  • 溶解度
    ——
  • SMILES
    CC(NCCCCCCNC(C)=O)=O
  • 化学全称
    1,6-Hexanebisacetamide

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1. Ketchart W, et al. Oncogene. 2013 Aug 15;32(33):3829-39.
2. Nilsson LM, et al. Cancer Res. 2016 Apr 15;76(8):2376-83.
3. Dey A, et al. Cell Cycle. 2008 Dec;7(23):3759-67.
产品手册
关联产品
  • BI-9564

    BI-9564 (BI9564) is a potent, selective, cell-permeable and noncytotoxic BRD9 bromodomain inhibitor with IC50 of 75 nM, Kd of <20 nM.

  • ABBV-744

    ABBV-744 (ABBV744) is a potent, BDII-selective BET bromodomain inhibitor.

  • HJB-97

    A potent BET bromodomian inhibitor with IC50 of 3-7 nM for BRD2/3/4 BD1 and BD2.